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Professional Summary
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Dr. Kasting is Professor of Pharmaceutics and Cosmetic Science at the James L . Winkle College of Pharmacy. He teaches in the College’s graduate and professional programs and conducts research in the area of percutaneous absorption. Prior to beginning an academic career in 1999, he served as a senior scientist with the Skin Beauty Care Technology Division of Procter & Gamble's Miami Valley Laboratories, working on the development of improved skin care products. He received his B.A. in Chemistry from Vanderbilt University in 1975 and his Ph.D. in Physical Chemistry from MIT in 1980. He has published over fifty papers in the above areas and holds eight patents associated with his work. He is a two-time recipient of the Shaw Mudge Award from the Society of Cosmetic Chemists and was the 2005 chair of the Gordon Research Conference on Barrier Function of Mammalian Skin. He serves on the Editorial Board of the Journal of Pharmaceutical Sciences and Pharmaceutical Research and Development and as a referee for several other major pharmaceutical journals. His current research is focused on the development of improved computational models for topical delivery and dermal risk assessment based on a mechanistic understanding of the percutaneous absorption process. Projects include development of microstructural models for transport through the stratum corneum and hair follicle, prediction of solvent and pesticide absorption and evaporation rates from skin, estimation of the epidermal bioavailability of contact allergens and quantification of the effects of water on skin and nail permeability.
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Research Support
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Grant #2 R01 OH007529
GB Kasting (PI); JM Nitsche; JC Kissel; RJ Soman
09/01/2007
08/31/2012
NIOSH/CDC
Mechanistically-Based in Silico Estimation of Dermal Absorption in the Workplace
Role:PI
$1,954,729
Active
Grant
National
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GB Kasting; GF Gerberick; P Kern
04/01/2005
03/31/2008
COLIPA A.I.B.S.
Development of a Toxicodynamic-Model to Better Predict Epidermal Bioavailability of Contact Allergens
Role:co-PI
120,000 Euros
Completed
Contract
International
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Keywords
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drug delivery, percutaneous absorption, membrane transport
,Transdermal Drug Delivery(MeSH TrDrgDel),Pharmacokinetics(MeSH PhrmKin),Physical Sciences(MeSH H),Natural Sciences(MeSH H01)
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Research and Practice Interests
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Development of computational models for absorption of materials into and through the skin with the objective of developing better tools for prediction of topical drug delivery, transdermal drug delivery, and dermal exposure to noxious agents.
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