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  Jianfei Guo
Assoc Professor
Pharmacy Practice and Admin Sciences - 0004
513-558-8613
guoje@ucmail.uc.edu


  Professional Summary

  Jeff J. Guo, PhD, has been mentoring several MS, PhD, and PharmD students, and teaching graduate courses, Pharmaceutical Economics & Policy, Pharmacovigilance and post-marketing evaluation, Research in Pharmacoepidemiology & Drug Safety, and Biostatistics for Pharmacist at UC. He is a founder for ISPOR Asian Consortium and past Chair for its Advisory Committee. He has been a member of editorial boards of journals American Health & Drug Benefit, Research in Social Administrative Pharmacy, and The Open Health Services & Policy. He has numerous book chapters and/or peer-reviewed publications in pharmacoeconomics and pharmacoepidemiology on topics including a physician prescribing behavior, drug-drug interaction, risk of diabetes associated with antipsychotics, cisapride and contraindicated medications, acute pancreatitis associated with antiretroviral medications, drug-induced hepatotoxicity, cost-of-illness analysis, a cost-benefit analysis for asthmatic medications, the measurement of quality in the practice of oncology, the costs to business of HIV/AIDS, drug control policy, drug price and market competition, as well as an evaluation of health outcomes for children who use school-based health centers.

  Research Support

  PI: Guo. Bristol-Myers Squibb Company. Epidemiology and Health Utilization Study for Patients with Bipolar Disorder in Managed Care Population.

  PI: Guo Health Foundation of Greater Cincinnati Evaluation of health utilization and outcomes for Medicaid recipients enrolled in School-Based Health Centers (SBHC).

  PI: Cluxton; Co-PI: Guo. Ohio Medicaid Agency Medicaid retrospective drug utilization review and health service research program for Ohio.

  PI: Guo. URC Acute pancreatitis associated with different combination therapies between HIV-infected patients in Medicaid.

  Guo (PI) Health Foundation of Greater Cincinnati Health-related Quality of Life and Cost-Effectiveness Analysis for School-Based Health Centers for Children and Adolescents

  Guo (PI) Janssen Pharma Drug-Drug Interaction Associated with Antipsychotics in Patients with Schizophrenia and/or Bipolar Disorder

  Heaton (PI), Co-Investigators: Guo JJ, Kelton CML, Martin J, Cavanaugh T. 06-2008 05-2009 Eli-Lilly Company "Economic cost and epidemiology for alcoholism and heavy alcohol drinkers" Active Grant

  Heaton (PI), Co-Investigators: Cluxton RC, Guo JJ. 07-2008 06-2009 Ohio Medicaid Agency “Retrospective drug utilization review for the Ohio State Medicaid program.” Active Grant


Publications
  Peer Reviewed Publications

 

Guo JJ, Wigle R. P, Lammers K, Vu O. (2005). Comparison of Potentially Hepatotoxic Drugs in Major US Drug Compendia. J Res Social & Administrative Pharmacy, 8(3), 460-479.

 

Guo JJ, Jang R, Louder A, Cluxton RJ. (2005). Acute Pancreatitis Associated with Different Drug Therapies among HIV-infected Patients. Pharmacotherapy, Vol 25(8), 1044-1054.

 

Guo JJ, Kelton CML, Pasquale MK, Zimmerman J, Patel A, Heaton PC, Cluxton RJ. (2004). Price and Market-Share Competition of Anti-Ulcer Gastric Medications in the Ohio Medicaid Market. Int J Pharmaceutical Medicine, Vol.18(5), 271-282..

 

Guo JJ. (2004). Book Review on Federal Drug Control: The Evolution of Policy and Practice. Erlen J, Spillance JF, eds. American J Pharm Educ, Vol.68(5), 124.

 

Guo JJ, Ludke RC, Heaton PC, Cluxton RJ. (2004). Charateristics and Risk Factor of High-Cost Recipients in the Ohio Medicaid Program. Managed Care Interface, Vol.17(10), 20-27.

 

Guo JJ, Jang R, Keller KK, McCracken A, Pan W, Cluxton RJ. Impact of School-Based Health Centers on Children with Asthma. J Adol Health. 2005, Vol.37(4), 266-274.

 

Liu GG, Guo JJ*, Smith SR. (2004). HIV/AIDS Epidemic and Economic Costs to Business. Pharmacoeconomics, Vol.22(18), 1181-1194.

 

Guo JJ, Curkendall S, Jones J, Fife D, Goehring E, She DW. (2003). The impact of cisapride label change on codispending of contraindicated medications. J Pharmacoepidemiology Drug Safety, (12), 295-301..

 

Johnston JA, Cluxton, RJ, Heaton PC, Guo JJ, Moomaw CJ, Eckman MH. (2003). Predictors of Warfarin Use among Ohio Medicaid Patients with New-Onset Nonvalvular Atrial Fibrillation. Arch Intern Med, (163), 1705-1710.

 

Jones JK, Fife D, Curkendall S, Guo JJ, et al. (2001). Coprescribing and codispensing of cisapride and contraindicated drugs. JAMA-Journal of American Medical Association, 286(13), 1607-1609.

 

Guo JJ, Gibson JT, Gropper DM, Oswald SL, and Barker KN. (1998). Empiric investigation on direct costs-of-illness and healthcare utilization of Medicaid patients with diabetes mellitus. American J Managed Care, Vol.4(10), 1433-1446.

 

Guo JJ, Diehl MC, Felkey BG, Gibson JT, and Barker KN. (1998). Comparison and analysis of the national drug code systems among drug information databases. Drug Information Journal, 32(3), 769-775.

 

Jing YH, Guo JJ*, Li X. (2006). Pregnancy registry research: FDA Guidance and Case Studies. Chinese Journal of Pharmacovigilance, 3(2), 72-80.

 

Guo JJ, Keck PE, Li H, Corey-Lisle PK, et al. (2006). Diabetes mellitus associated with antipsychotic use among patients with bipolar disorders: a population-based case-control study. J Clin Psych, 67(7), 1055-1061.

 

Chen Y, Guo JJ. (2006). Meta-analysis of antidepressant treatments for patients with post-stoke depression. Stroke, 37(6), 1365-1366.

 

Chen Y, Guo JJ, Jiang DM, Zhang SY. (2006). Data mining methods for signals of drug adverse reactions [Part 1][Part 2]. Chinese Journal of Pharmacoepidemiology, 15(1), 43-46.

 

Jing YH, Guo JJ*, Li X. (2005). Risk Management Guidance and Case Studies for Drug Administration. Chinese Journal of Pharmacovigilance, 2(4), 193-200.

 

Neuss MN, Desch CE, McNiff KK, Eisenberg PD, Guo JJ, et al. (2005). A process for measuring the quality of cancer care: the quality oncology practice initiative (QOPI). J Clin Oncology, 23(25), 6233-9.

 

Guo JJ, Gibson JT, Hancock GR, and Barker KN. (1995). Retrospective drug utilization review and the behavior of Medicaid prescribers: an empirical analysis. Clinical Therapeutics, 17(6), 1174-87.

 

Jing YH, Kelton CML, Guo JJ*, Chen Y, Li X, Wigle PR. (2006). Price and utilization of HMG Co-A reductase inhibitors (Statins) in the US Medicaid program. Drug Benefit Trends, 18(11), 580-592.

 

Chen Y, Guo JJ, Zhang S. (2006). Treatment effect of antidepressants for patients with post-stroke depression: a meta-analysis. Annals of Pharmacotherapy, 40(12), 2115--2122.

 

Heaton PC, Guo JJ, Cluxton RC, Jang R, Horning R. (2006). Analysis of the effectiveness and cost benefit of leukotriene modifiers in adults with asthma in the Ohio Medicaid population. J Manag Care Pharm, 12(1), 33-42.

 

Dusting ML, Guo JJ, Kelton CML, Pasquale MK. (2005). Competition and Price Discounts in Anti-Infective Pharmaceutical Markets in the United States. Journal of Pharmaceutical Finance, Economics & Policy, 14(2), 59-85.

 

Guo JJ, Keck PE, Li H, Corey-Lisle PK, Jiang DM, Jang R, L’Italien GJ. (2007). Diabetes associated with antipsychotic use among Medicaid patients with bipolar disorders: a nested case-control study. Pharmacotherapy, 27(1), 27-35.

 

Kelton CML,Dusing ML, Ferrand Y, Rebelein RP, Guo JJ. (2007). Analysis of Pharmaceutical Products with Large Price Changes in Regional Hospital System. J Pharm Fin Econ Policy, 16(2), 61-86.

 

Jing YH, Kelton CML, Li X, Guo JJ. (2007). Lethal drug probe in China – a case of Xinfu clindamycin. Pharmacoepidemiology Drug Safety, (16), 928--932..

 

Chen Y, Patel NC, Guo JJ, Zhan S. (2007). Antidepressant prophylaxis for poststroke depression: a meta-analysis. International Clinical Psychopharmacology, 22(3), 159-166.

 

Chen Y, Guo JJ, Healy D, Zhang S. (2007). Effect of integrated traditional Chinese medicine and Western medicine on SARS treatment: a meta-analysis study. Pharmacy Practice, 5(1)), 1-9.

 

Li X, Jing Y, Guo JJ. (2007). The reintroduction of natalizumab and its risk management plan. Chinese J Pharmacovigilance, 4(1)), 14-17.

 

Jing YH, Kelton CML, Guo JJ, Chen Y, Li X, Patel NC. (2007). Drug utilization, price, and market-share competition among antipsychotics in US Medicaid programs. Drug Benefit Trends, 19(1), 27-41.

 

Jing Y, Li X, Guo JJ. (2006). Drug-induced hepatotoxicity and FDA white papers. Chinese Journal of Pharmacovigilance, 3(6), 325-328.

 

Du W, Jing Y, Kelton CML, Guo JJ. (2007). Analysis and comparison of post-marketing surveillance between China and other countries. Value in Health, Suppl., 11(1), S130--S136.

 

Guo JJ, Keck PE, Li H, Patel NC. (2007). Bipolar-related and comorbidity treatment costs for patients with bipolar disorder in Medicaid. Psych Services, 58(8), 1073-1078.

 

Jing Y, Klein P, Kelton CML, Li X, Guo JJ. (2007). Drug price, utilization, and spending of antiretroviral medication in the U.S. Medicaid programs. AIDS Research & Therapy, 4(22), 1-8.DOI:Available online: http://www.aidsrestherapy.com/

 

Jing Y, Li X, Guo JJ. (2007). Medicaid cost containment strategies in US. Chinese Journal of Pharmaceutical Economics., 3, 73-77.

 

Kelton CML, Ferrand Y, Heaton PC, Guo JJ. (2008). Impact of health policy on use of antidepressant drug in the US Medicaid program. J Mental Health Policy Economics. 11(1), 35--49..

 

Wade TJ, Keller KN, Guo JJ, Huentelman T, Line K, Mansour ME (2008). Access and utilization patterns across the first three years of implementation of elementary and middle school school-based health centers. Public Health Reports, 123(6), 739-750.

 

Guo JJ, Wade TJ, Keller KN. (2008). Impact of School-Based Health Centers on Students with mental health problems. Public Health Reports, 123:(5), 768-80.

 

Chen Y, Patel NC, Wulsin L, Guo JJ (02-2008). Risk of Cerebral Vascular Diseases associated with antidepressant use in a large managed care population: population-based case-control study. Annals Pharmacotherapy, 42(2:), 177-184.Co-Author

 

Guo JJ (2008). Schizophrenia associated with increased risk of colon cancer but reduced risk of respiratory cancer. [Commentary]. Evidence-Based Mental Health, 11(3), 93..Author

 

Chen Y, Guo JJ, Li H, Patel NC (2009). Hemorrhagic stroke associated with antidepressant use in patients with depression: does degree of serotonin reuptake inhibition matter?. Pharmacoepidemiol Drug Saf, 18(3), 196--202..Co-Author

 

Chen Y, Kelton CML, Jing YH, Li X, Guo JJ (2008). Trend analyses of utilization, price, and spending for antidepressant drugs in the US Medicaid program. J Res Social Administrative Pharmacy, 4:, 244-257.Co-Author

 

Guo JJ, Keck PE, Li H, Jang R, Kelton CML (2008). Treatment costs and health utilization for patients with bipolar disorder in a large US managed care population. Value in Health, 11(3), 416-423.

 

Chen Y, Guo JJ, Healy D, Patel NC (2008). Risk of Hepatotoxicity Associated with the Use of Telithromycin: Signal Detection Based upon the FDA’s Spontaneous Reporting System. Annals Pharmacotherapy, 42(12:), 1791--6.Co-Author

 

Demland J, Jing Y, Kelton CML, Guo JJ, Li H, Wiggle PR (2009). Drug utilization pattern and off-label use of atypical antipsychotics in patients with bipolar disorder: 1998-2002. Am Health Drug Benefit, 2(4), 184--191..Author

 

Chen Y, Guo JJ**, Steinbuck M, Lin XD, Buncher CR, Patel C. (2008). Comparisons of Data Mining Algorithms for Adverse Drug Reactions: An Empirical Study based on the Adverse Event Reporting System of the Food and Drug Administration. J Pharm Med, 22(6), 359--65.

 

Guo JJ, Kelton CML. (2009). The role of epidemiology for drug development. Am Health Drug Benefit., 2(1 supplement), S49--54.Author

 

Roddy J, Partridge S, Rockey M, Pruemer J, Guo JJ, Desai S, Safa M. (2009). (In Press).Thromboembolic Events in Patients with Colorectal Cancer Receiving the Combination of Bevacizumab-based Chemotherapy and Erythropoietin Stimulating agents. J Clinical Oncology.

 

Huang S, Wulsin L, Li H, Guo JJ. (2009). Dimensionality Reduction for Knowledge Discovery in Medical Claims Database: Application to Antidepressant Medication Utilization Study. Computer Methods and Programs in Biomedicine, 93:, 115--123.

 

Guo JJ, Jing Y, Nguyen K, Fan H, Li X, Kelton CM (2008). Principal components analysis of drug utilization and expenditure trends for major therapeutic classes in U.S. Medicaid programs. Journal of Medical Economics, 11:(671-), 694.Author

  Other Publications

 

Guo JJ, Ludke RL, Heaton PC, Moomaw CJ, Ho M, Cluxton RJ. (2003). Characteristics and Utilization Patterns of High-Cost Recipients in Medicaid Population: a final report to Medicaid MEDTAPP program, the Ohio Department of Jobs & Family Services. Columbus, Ohio. Website available at: http://jfs.ohio.gov/OHP/bhpp/Medtapp.stm -[112 pages].

 

Guo JJ, Ludke RL, Cluxton RJ, Moomaw CJ, Ho M, Heaton PC, Hornung RW. (2003). Characteristics and Risk Factors for Hospital Readmission. Final report to Medicaid MEDTAPP program, the Ohio Department of Jobs & Family Services. Columbus, Ohio. Website available at: http://jfs.ohio.gov/OHP/bhpp/Medtapp.stm -[69 pages].

 

Guo JJ, Jang R, Cluxton RJ, et al. (2005). A Prescription for Success: How School-Based Health Centers Affect Health Status and Health Use and Cost: a final Report. The Health Foundation of Greater Cincinnati, Cincinnati, Ohio. Website available at: http://www.healthfoundation.org/ -102 pages.

  Book Chapter

 

Guo JJ, Kelton C. (2007). Handbook of Pharmaceuticfal Public Policy. In Fulda T, Wertheimer A, eds.(Eds.), Patent protected brand-name drugs and competition between brand-name and generic drugs. [Chapter 20]. (pp. 395--416). New York: Haworth Press Inc..Co-Author

 

Guo JJ. (2001). Traditional Chinese Medicine and Natural Products. Cost-effectiveness and drug safety: critical success factors of Chinese traditional medicine and natural medicine. (pp. 72-74). Hong Kong, China: Times Resource Publishing Ltd..Author

 

Guo JJ, Jones JK. (2008). Pharmacoepidemiology and Therapeutic Risk Management. In Hartzema AG, Tilson HH, Chen A eds.(Eds.), Chapter 29: The Story of cisapride and Its Withdraw from Market: A Case Study. (pp. p727--738). Cincinnati, Ohio: Harvey Whitney Books.

  Honors and Awards

  -2/07/2005 Chair-Elect. ISPOR Asian Consortium Advisory Committee.

  2006 Best Poster Presentation Award at the International Society of Pharmacoeconomics & Outcomes Research Conference.

  2000 The First Prize of Presentation International Society of Pharmacoepidemiology at Spain

 

  Research and Practice Interests

  Pharmacoeconomics, health outcomes, pharmacoepidemiology, drug utilization review, drug safety and pharmacovigilance, pharmaceutical policy, clinical informatics, analysis of medical record and claims databases

  Courses Taught

  25-PADM-611 STATISTICS FOR PHAR Application of Statistics for Pharmacists Level:Graduate Service Learning:No Course# 25PADM611 and #25PADM648 (NTPD), 3 credit hours, Application of Statistics for Pharmacists

  25-PHDD-705 PHARMVIG & PM SURV Pharmacovigilance and Post-Marketing Surveillance Actual Enroll:8 Level:Graduate Service Learning:No 25PHDD705, “Pharmacovigilance and Post-Marketing Surveillance”, 3 credit hours, Course Coordinator.

  25-PADM-571 INTRO PHARM ECON & POLICY Pharmaceutical Economics and Policy Level:Graduate Service Learning:No Course# 25PADM 571, 3 credit hours, “Pharmaceutical Economics and Policy”, Course Coordinator

  25-PADM-672 RESPHARMACOEPIDEMOL Research in Pharmacoepidemiology and Drug Safety Level:Graduate Service Learning:No Course 25PADM672 - “Research in Pharmacoepidemiology and Drug Safety.” Course Coordinator.

  25-PHID-743 RESEARCH PHARM SCI Research Topics in Pharmaceutical Sciences Level:Graduate Service Learning:No Course 25PHID743 - Research Topics in Pharmaceutical Sciences. Offered it for all our graduate students in Fall, Winter, and Spring quarters.

  25-PHID-971 PHD DISSERTATN RES PhD Dissertation Research Level:Graduate Service Learning:No Course 25PHID971 PhD Dissertation Research. Offered it for our graduate students in Fall, Winter, and Spring quarters.

  Graduate Seminar in Pharmaceutical Sciences (Social Administrative Sciences 25-PADM-701 Level:Graduate Service Learning:No Course 25PADM701 - Graduate Seminar in Pharmaceutical Sciences (Social Administrative Sciences).




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